Instrumentation

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ACTA offers comprehensive analytical services to support your testing needs.  The following is a list of the USP General Chapter tests performed at ACTA. 

Chromatography
  • High Performance Liquid Chromatography (HPLC) with the following detection capabilities:
    • UV/Visible absorbance
    • Fluorescence
    • Photo Diode Array
    • Refractive Index
    • Conductivity
    • Post-Column Derivatization
  • Ion Chromatography (IC)
  • Gas Chromatography (GC) with Direct Injection and Headspace Injection (FID detection)
  • High Performance Liquid Chromatography coupled with an Inductively Coupled Plasma Mass Spectrometer (HPLC-ICP-MS)

 

Elemental Testing Equipment
  • Inductively Coupled Plasma Mass Spectrometer (ICP-MS)
  • High Performance Liquid Chromatography coupled with an Inductively Coupled Plasma Mass Spectrometer (HPLC-ICP-MS).

 

 

Stability Chambers

ACTA has a standby generator that maintains power to the stability chambers in the event of a power failure and an alarm system that will page the Director of QA/QC in the event that any stability chamber fails to maintain its humidity or temperature setpoints. These controls ensure that stability samples will be stored as required.

Stability Chambers are maintained at the following conditions:

ICH Conditions:

  • 25° C / 60% RH
  • 30° C / 65% RH
  • 40° C / 75% RH


ISO Accelerated Storage for Medical Devices
  • 45° C / > 40% RH


And at these conditions:
  • 2 to 8° C
  • -25 to -10° C
We also provide custom temperature and humidity conditions based on your specific needs.
General Chemistry Equipment
  • UV/Visible Spectrophotometer (UV/Vis)
  • Fourier Transform Infrared Spectrophotometer (FTIR)
  • Fluorescence Spectrophotometer
  • Polarimeter, High sensitivity capable of all USP wavelengths (325, 365, 405, 436, 546, 577, and 589 nm)
  • Osmometer
  • Refractometer
  • Karl Fischer Titrator
  • Karl Fischer Coulometer
  • Melting Point Apparatus
  • Brookfield Viscometer
  • Total Organic Carbon Analyzer (TOC Analyzer)
  • Conductivity Meter
  • Ion Specific Electrode Meter
  • Dissolution Apparatus
  • Disintegration Apparatus
  • Light Obscuration Particle Counter (For USP<788>)
  • Differential Scanning Calorimeter (DSC)

 

 

General Microbiology Equipment
  • Steam Sterilizer
  • Biological Safety Cabinet
  • Laminar Flow Hood
  • Microscope
  • Darkfield Colony Counter
  • Kinetic Chromogenic Bacterial Endotoxin Machine (LAL)